Leukemia is a neoplasm of acute or chronic blood-forming cells in bone
marrow and spleen (Reeves, 2001). The other characteristic of leukemia
is the proliferation of irregular or accumulation of white blood cells
in bone marrow, replace normal bone marrow elements. Proliferation also
occurs in the liver, spleen, and lymph nodes. The invasion of
non-haematological organs such as the meninges, gastrointestinal tract,
kidney, and skin.Acute lymphocytic leukemia (ALL) often occurs in children. Leukemia classified as acute if there is proliferation of the blastocyst (young blood cells) from bone marrow. Acute leukemia is a malignant primary bone marrow resulting in normal blood components late decision by abnormal blood components (blastocyst), accompanied by the spread of other organs. Leukemia is classified as chronic if found cell expansion and accumulation of old and young cells (Tejawinata, 1996).
In addition to acute and chronic, there is also a congenital leukemia is leukemia were found in infants aged 4 weeks or younger infants.
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